Medical & pharma

COLLIN Medical Line

Tube, film and compounding lines for medical and pharmaceutical plastics.

  • 8 machine families
  • Mono & multi-lumen tubing
  • COLLIN · Germany
At a glance

Published figures

< 100 µmMinimum tube diameter
Up to 5 mmMaximum tube diameter
Up to 5Tube layers
Up to 7Separate channels
Overview

Medical Line — what it covers

COLLIN Medical Line Compounders

The Medical Line is COLLIN's range for medical and pharmaceutical plastics processing, where the geometry tolerances and the documentation requirements are both tighter than general extrusion.

The headline capability is tube extrusion: mono and multi-lumen tubes in up to five layers with up to seven separate channels, at diameters from thinner than a human hair — under 100 µm — up to roughly 5 mm.

The range

8 machine families in the Medical Line

COLLIN Medical Line Compounders

Medical Line Compounders

pharmaceutical & medical technology Extremely short material changes

The COLLIN Medical Compounders are used for different applications in the pharmaceutical and medical technology. Due to the compact design, the lines can easily be cleaned and short material changes are possible. Highest precision, narrow tolerances, cleanness, process accuracy, good cleaning handling, clean-room conformity, quick and good service and custom-made customer trainings are a matter of course.

Materials: Polymers, Thermoplasts, ElastomersApplications: Drug incorporation into the carrier materials, Degassing of volatile materials, Pelletizing of tablet pre-mixtures
  • Manufactured according to FDA 21 CFR, ISPE, ISO 13485, Din EN 10204/3.1B, cGMP/GMP
  • The design meets the hygienic standards
  • Easy disassembly and cleaning
  • Enormous variability in production
  • Continuous production, compliance of all tolerance specifications
  • Lines, which can produce round the clock

Technical data

Parameters / compoundersZK 25 PZK 35 P
Nominal diatmeter25 mm35 mm
Torque per shaft110 Nm300 Nm
Max. speed1200 rpm1200 rpm
COLLIN Flat Film Lines P

Flat Film Lines P

for medical technology & pharmacy Production of thin-walled or heavy-wall films

These versions combine finishing calender and the chill roll and are used for the production of thin-walled or heavy-wall films. The 3-roll unit can be used for vertical or horizontal operation. The forces in the polishing gap can be created in a hydraulic or pneumatic way. The polishing roll is suitable for a wide range of applications such as smoothing, embossing or laminating.

Technical data

Parameters / Flat film linesFlat film line with 3 rolls
Web speed1-50 m/min, other speeds on request
Roller width200, 400, 600 mm
Working position rollshorizontal, vertical
COLLIN Blown Film Lines P Professional

Blown Film Lines P Professional

for medical technology & Pharmacy Mono and multi-layer products, tests, development, quality control

Blown film lines are used for function tests of polymers and compounds, for the development of multi-layer films, quality control for colour distribution, control of the dispersing behaviour of compounders and extruders or for the production of small film hoses in the food and medical sector.

Applications: Development of multi-layer films, Quality control for colour distribution, Control of dispersing behaviour of compounders and extruders
  • Compact design
  • Easy operability
  • Exact, reproducible movements
  • Quick changes of products and parameters
  • The design meets the hygienic standards
  • Easy disassembly and cleaning

Technical data

Parameters / Blown Film LinesBL 600 PBL 800 PBL 1000 P
Roll & roller width600 mm800 mm1000 mm
Max. web width590 mm790 mm990 mm
Web speed1-50 m/min1-50 m/min
COLLIN Extruders for Medical Technology

Extruders for Medical Technology

pharmacy & food GMP, FDA & SCADA

For medical technology, pharmacy as well as food (also pet), the Medical Extruder Line presents itself as compact and modular. The COLLIN Medical Line lines are explicitly adapted, designed and manufactured according to the respective customer requirements.

Materials: Various polymers, which are used in the medical sector, for example Pebax, EVA, Elastomers, PTFE, PVC etc.Applications: Multi-layer strand production, Mono & multi-lumen hoses, Mono & multi-layer applications
  • Innovative drive – compact gear motor or high torque motor
  • Manufactured according to FDA 21 CFR, ISPE, ISO 13485, Din EN 10204/3.1B, cGMP/GMP
  • The design meets the hygienic standards
  • Enormous variability for production of different products
  • Easy disassembly and cleaning
  • Development work for customers as well as pre-tests in the Collin Lab

Technical data

Parameters / ExtruderE 12 PE 16 PE 20 PE 25 PE 30 PE 45 PE 60 P
Cylinder Nominal diameter12 mm16 mm20 mm25 mm30 mm45 mm60 mm
Dimensions L x W x H1330 x 680 x 1650 mm1330 x 680 x 1650 mm1330 x 680 x 1650 mm1620 x 500 x 1600 mm1840 x 680 x 1650 mm2330 x 780 x 1800 mm3100 x 1200 x 2000 mm
COLLIN Presses for Medical & Pharma

Presses for Medical & Pharma

process accuracy,clean room conformity

They are manufactured according to the guidelines of the FDA 21 CFR, ISPE, ISO 13485, DIN EN 10204/3.1B, cGMP/GMP.

Applications: Clean-room technology – design for the production of medical or pharmaceutical products, Quality control of materials, Production of test sheets/samples
  • Highest precision
  • Tight tolerances
  • Cleanness
  • Process accuracy
  • Good cleaning handling
  • Clean room conformity

Technical data

PressesP 200 SP 300 SP 400 SP 500 S
Usable pressing area196 x 196 mm296 x 296 mm396 x 396 mm496 x 496 mm
Pressing force125 kN300 kN500 kN785 kN
Dimensions L x W x H1400 x 800 x 1800 mm1655 x 800 x1800 mm2000 x 9450 x 2050 mm2425 x 1050 x 2350 mm
COLLIN Tube lines

Tube lines

Mono & multi-lumen tubes for medical applications Up to 5 layers & 7 separate channels

COLLIN tube lines are used for the production of multi-lumen resp. plastic tubes for medical applications, also multi-layer. The spectrum of diameters ranges from thinner than a human hair (<100 µm) up to approx. 5 mm. By means of coextrusion, the properties of the tubes, with a design of up to 5-layers, are adapted to the requirements of the field of applications.

Materials: PVC, Polyethylene, Crosslinked PE, Silicone RubberApplications: Minimally invasive surgeries, Dialysis tubes, Infusion tubes
  • Up to 5 layers
  • Up to 7 separate channels
  • Manufactured according to FDA 21 CFR, ISPE, ISO 13485, Din EN 10204/3.1B, cGMP/GMP
  • Construction & design correspond to the hygienic standards
  • Easy cleaning
  • Enormous variability in production
COLLIN Calenders / Roll Mills

Calenders / Roll Mills

for pharmacy & medical technology Modular, compact, accurate

Calenders and roll mills are essential elements for the prototype production in pharmaceutical product development or for the production of tablets in all shapes and sizes. Small COLLIN Medical Line Calenders are designed for the production of small series, mainly in the pre-clinical selection phase. They can perfectly be combined with the small compounders.

Applications: Drug carrier, Tablet production, Prototype production
  • Manufactured according to FDA 21 CFR, ISPE, ISO 13485, Din EN 10204/3.1B, cGMP/GMP
  • The design meets the hygienic standards
  • Enormous variability for production of different products
  • Extremely accurate rotation and co-rotation of both rolls
  • Easy cleaning
COLLIN Strand Lines

Strand Lines

Complete lines for medical strands Exact roundness & exact diameter by vertical water bath

In case of COLLIN strand lines, it is unique that all production steps are provided by a single source – compounding, coextrusion, take-off and cut. The vertical water bath is the highlight – a COLLIN innovation, which guarantees reliable roundness. For an exact throughput of the line, the extruders are equipped with melt pumps and pressure/speed controls.

Materials: EVA, TPE, TPUApplications: Medical yarn, Drug-loaded strands
  • All production steps from one source
  • Reliable roundness and diameter by vertical water bath
  • Different take-off speeds
  • Manufactured according to FDA 21 CFR, ISPE, ISO 13485, Din EN 10204/3.1B, cGMP/GMP
  • The design meets the hygienic standards
  • Easy cleaning
Applications

Where the Medical Line is used

Catheters Multi-lumen medical tubing Medical packaging film Wound dressings Pharmaceutical compounding Drug-eluting devices
K Group support

COLLIN in Pakistan — through K Group

K Group is the authorized agent for COLLIN Lab & Pilot Solutions in Pakistan. Tell us the material, the throughput and what you are trying to prove, and we will size the line and quote it — including downstream equipment, dies and the instrumentation to measure the result.

Line specification and sizing Downstream equipment selection Installation and commissioning Operator training Spare parts and service
Complete the line

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